GALBRUN, Diane (2016) Modélisation et analyse patient-spéciﬁque de la cinématique de la paroi carotidienne sur séquences d’images ultrasonores PFE - Project Graduation, ENSTA.
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This study aims at providing complementary tools to prevent cardiovascular events. The goal is to characterize an early and patient-speciﬁc state of cardiovascular risk, by an analysis of carotid wall kinematics. Methods This study uses echographic videos and sets of medical data. It is based on a biomechanical model of elastic arteries, image processing (vessel segmentation and motion tracking), and object-oriented data processing. Results The group of people can be separated according to a precise score, or according to a proﬁle. Both are representative of a given cardiovascular risk. Two kinematics come out as distinguishable, and characterize one mechanical state reﬂecting medical condition : radial kinematics and longitudinal kinematics. The maximum thickness of the vessel inner layers is 684 µm, and the mean of the radial movement amplitude is of 12,1%. Furthermore, it has been found that a state of patient-speciﬁc cardiovascular risk is not independent from given longitudinal kinematics. Diﬀerenciating typical kinematics (and thus, associated states of risk) is achieved by diﬀerenciating shapes of longitudinal motion. Interpretations are oﬀered. They can be conﬁrmed by a further improvement of the implemented image processings. Conclusion Results encourage a temporal monitoring of wall motions, to diﬀerentiate populations in terms of cardiovascular risk. THe amound of exploited data does not allow to conclude in a statistically signiﬁcant way about quantitative values. Nevertheless, the study oﬀers methods to continue to work on and resolve the objective.
|Item Type:||Thesis (PFE - Project Graduation)|
|Subjects:||Information and Communication Sciences and Technologies|
Life Sciences and Engineering
|Deposited By:||INVALID USER|
|Deposited On:||19 oct. 2016 15:48|
|Dernière modification:||19 oct. 2016 15:48|
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